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Figure 5: Tert-butylhydroquinone alleviates insulin resistance in HepG2 cells through AMPKα2/PI3K/AKT signaling. GLUT4 (a), GSK3β (b), phosphorylated PI3K (c) and phosphorylated AKT (d) amounts in HepG2 cells are shown. *P < 0.05 versus Control group; &P < 0.05 versus HClO + insulin group; #P < 0.05 versus siPRKAA2 + Control group; $P < 0.05 versus siPRKAA2 + HClO + insulin group; ^P < 0.05 versus siPRKAA2 + HClO + Tert-butylhydroquinone + insulin group. Data are mean ± standard deviation (n = 3)

Figure 5: Tert-butylhydroquinone alleviates insulin resistance in HepG2 cells through AMPKα2/PI3K/AKT signaling. GLUT4 (a), GSK3β (b), phosphorylated PI3K (c) and phosphorylated AKT (d) amounts in HepG2 cells are shown. <i>*P </i>< 0.05 versus Control group; <sup>&</sup><i>P </i>< 0.05 versus HClO + insulin group; <sup>#</sup><i>P </i>< 0.05 versus siPRKAA2 + Control group; <sup>$</sup><i>P </i>< 0.05 versus siPRKAA2 + HClO + insulin group; <sup>^</sup><i>P </i>< 0.05 versus siPRKAA2 + HClO + Tert-butylhydroquinone + insulin group. Data are mean ± standard deviation (<i>n</i> = 3)