Indian J Pharm Close
 

Figure 1: Effect of NIM on PASI scoring, IMQ induced skin epidermal thickness, and splenomegaly. Objective scoring accounting for redness (erythema), skin thickness, and scaling on a scale of 0 to 4, where 0 represents none, 1 represents mild, 2 represents moderate, 3 represents severe and 4 represents very severe. (a) Representative graph of PASI scoring, (b) Morphological representation of skin epidermis of mice dorsum and spleen of all experimental groups on termination day, (c) Graphical presentation of spleen body weight index. ****P < 0.0001 of IMQ versus Normal Control; ^^^^P < 0.0001 of NIM versus IMQ. IMQ=Imiquimod, PASI=Psoriasis Area Severity Index, NIM=Nimbolide

Figure 1: Effect of NIM on PASI scoring, IMQ induced skin epidermal thickness, and splenomegaly. Objective scoring accounting for redness (erythema), skin thickness, and scaling on a scale of 0 to 4, where 0 represents none, 1 represents mild, 2 represents moderate, 3 represents severe and 4 represents very severe. (a) Representative graph of PASI scoring, (b) Morphological representation of skin epidermis of mice dorsum and spleen of all experimental groups on termination day, (c) Graphical presentation of spleen body weight index. ****<i>P</i> < 0.0001 of IMQ versus Normal Control; ^^^^<i>P</i> < 0.0001 of NIM versus IMQ. IMQ=Imiquimod, PASI=Psoriasis Area Severity Index, NIM=Nimbolide