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Figure 8: Effect of ovariectomy on acetylcholine-induced endothelium-dependent relaxation (a) and sodium nitroprusside-induced endothelium-independent relaxation on isolated aortic ring preparation (b) after 1, 2, and 3 months. Responses are expressed as percentage of maximum contraction induced by phenylephrine (3 × 10−6 M). Data are expressed as mean ± standard error of mean. (*) P < 0.05 versus sham

Figure 8: Effect of ovariectomy on acetylcholine-induced endothelium-dependent relaxation (a) and sodium nitroprusside-induced endothelium-independent relaxation on isolated aortic ring preparation (b) after 1, 2, and 3 months. Responses are expressed as percentage of maximum contraction induced by phenylephrine (3 × 10<sup>−6</sup> M). Data are expressed as mean ± standard error of mean. (*) <i>P</i> < 0.05 versus sham