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Figure 2: Effect of metabolic syndrome on hippocampal acetylcholine esterase activity and glutathione levels. (a) Metabolic syndrome led in significant increase in hippocampal acetylcholine esterase activity compared to control. While treatment with minocycline partially reversed metabolic syndrome-associated increase in hippocampal acetylcholine esterase activity (b) metabolic syndrome led to significant decrease in hippocampal glutathione levels compared to control. While treatment with minocycline successfully reversed metabolic syndrome associated decrease in glutathione levels. ***P < 0.001, **P < 0.01 all values are expressed as mean ± standard error of the mean for n = 10

Figure 2: Effect of metabolic syndrome on hippocampal acetylcholine esterase activity and glutathione levels. (a) Metabolic syndrome led in significant increase in hippocampal acetylcholine esterase activity compared to control. While treatment with minocycline partially reversed metabolic syndrome-associated increase in hippocampal acetylcholine esterase activity (b) metabolic syndrome led to significant decrease in hippocampal glutathione levels compared to control. While treatment with minocycline successfully reversed metabolic syndrome associated decrease in glutathione levels. ***<i>P</i> < 0.001, **<i>P</i> < 0.01 all values are expressed as mean ± standard error of the mean for <i>n</i> = 10