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Figure 2: (a) Typical tracing showing contractile effect of 5-hydroxytryptamine (10-9−10-3 M) on the spontaneous contractions in isolated rat fundus. (b) Typical tracing showing inhibitory effect of Zanthoxylum alatum n-hexane extract (30, 100, 300, and 1000 μg/ml) on the spontaneous contractions in isolated rat fundus. (c) Comparison of dose–response curves of 5-hydroxytryptamine in the absence and presence of antagonist ketanserin and Zanthoxylum alatum n-hexane extract on isolated rat fundus. Values are mean ± standard error mean (n = 4)

Figure 2: (a) Typical tracing showing contractile effect of 5-hydroxytryptamine (10<sup>-9</sup>−10<sup>-3</sup> M) on the spontaneous contractions in isolated rat fundus. (b) Typical tracing showing inhibitory effect of <i>Zanthoxylum alatum</i> n-hexane extract (30, 100, 300, and 1000 μg/ml) on the spontaneous contractions in isolated rat fundus. (c) Comparison of dose–response curves of 5-hydroxytryptamine in the absence and presence of antagonist ketanserin and <i>Zanthoxylum alatum</i> n-hexane extract on isolated rat fundus. Values are mean ± standard error mean (<i>n</i> = 4)