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Figure 2: Effect of acidosis on α-1 agonist (noradrenaline and phenylephrine).induced concentration-related contractile response curve in goat superior mesenteric artery. (a) Noradrenaline (1 nM-100 μM)-induced concentration-related contractile response curve elicited at pHo 7.4, 6.8, 6.0, 5.5, 5.0, and 4.5. (b) Phenylephrine (1 nM-100 μM)-induced concentration-related contractile response curve elicited at pHo 7.4, 6.8, 6.0, 5.5, 5.0, and 4.5. Data were expressed as mean gram tension ± standard error. *P < 0.05 versus pH 7.4 (control)

Figure 2: Effect of acidosis on α-1 agonist (noradrenaline and phenylephrine).induced concentration-related contractile response curve in goat superior mesenteric artery. (a) Noradrenaline (1 nM-100 μM)-induced concentration-related contractile response curve elicited at pH<sub>o</sub> 7.4, 6.8, 6.0, 5.5, 5.0, and 4.5. (b) Phenylephrine (1 nM-100 μM)-induced concentration-related contractile response curve elicited at pH<sub>o</sub> 7.4, 6.8, 6.0, 5.5, 5.0, and 4.5. Data were expressed as mean gram tension ± standard error. <i>*P</i> < 0.05 versus pH 7.4 (control)