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Figure 4: Concentrations of 6-mercatopurine after oral administration of azathioprine (50 mg/kg) at 2 h and 6 h (a) Duodenal homogenate; (b) liver homogenate results are reported as mean ± standard error of mean (n = 3). Statistical analysis was performed by using two-way analysis of variance (time and treatment as main factors) followed by Bonferroni's test as a post hoc analysis to identify significant differences among the two groups. *P < 0.05, **P < 0.01, and ***P < 0.001 when compared with the corresponding time reading of the vehicle control group

Figure 4: Concentrations of 6-mercatopurine after oral administration of azathioprine (50 mg/kg) at 2 h and 6 h (a) Duodenal homogenate; (b) liver homogenate results are reported as mean ± standard error of mean (<i>n</i> = 3). Statistical analysis was performed by using two-way analysis of variance (time and treatment as main factors) followed by Bonferroni's test as a <i>post hoc</i> analysis to identify significant differences among the two groups. *<i>P</i> < 0.05, **<i>P</i> < 0.01, and ***<i>P</i> < 0.001 when compared with the corresponding time reading of the vehicle control group