Figure 1: Histopathology of small intestinal tissue (a) vehicle control – duodenum (×100); (b) Vehicle control – duodenum (×400) (c) vehicle control – jejunum (×100); (d) Vehicle control – jejunum (×400) (e) methotrexate-treated – duodenum (×100); (f) methotrexate-treated – duodenum (×400) (g) methotrexate-treated – jejunum (×100); (h) methotrexate-treated – jejunum (×400) Key: Mu = Muscle layer, V = Villi, C = Crypts, M = Mucosa, Su = Longitudinal smooth muscle layer, G = Goblet Cells, N = Necrosis, I = Infiltration, Ex = Exocytosis and VC = Villous Collapse