Indian J Pharm Close
 

Figure 1: Frequency histogram plot of metabolic ratio. Metabolic ratios were determined as the ratio of the concentration of metabolite to parent drug for each patient, and the histogram of metabolic ratio for each study participant is plotted here. The median metabolic ratio obtained was 0.2, and the distribution looks such as normal distribution suggesting the absence of any polymorphism in the cytochrome P450 2E1 gene

Figure 1: Frequency histogram plot of metabolic ratio. Metabolic ratios were determined as the ratio of the concentration of metabolite to parent drug for each patient, and the histogram of metabolic ratio for each study participant is plotted here. The median metabolic ratio obtained was 0.2, and the distribution looks such as normal distribution suggesting the absence of any polymorphism in the cytochrome P450 2E1 gene