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Figure 1: Effects of polyphenolic fraction of Desmostachya bipinnata on Tamoxifen- induced liver damage in rats-histopathology (stained with hematoxylin and eosin): (a) Normal group, normal cellular architecture with distinct hepatic cells (10×). (b) TAM-intoxicated group, feathery degeneration with necrosis and vacoulation (40×). (c) Silymarin (100 mg/kg) + Tamoxifen-treated group, less necrosis and vacoulation (40×). (d) PFDB (100 mg/kg) + Tamoxifen-treated group (40×). (e) PFDB (200 mg/kg) + Tamoxifen-treated group, increased number of hepatocytes with normal nucleus (40×)

Figure 1: Effects of polyphenolic fraction of <i>Desmostachya bipinnata</i> on Tamoxifen- induced liver damage in rats-histopathology (stained with hematoxylin and eosin): (a) Normal group, normal cellular architecture with distinct hepatic cells (10×). (b) TAM-intoxicated group, feathery degeneration with necrosis and vacoulation (40×). (c) Silymarin (100 mg/kg) + Tamoxifen-treated group, less necrosis and vacoulation (40×). (d) PFDB (100 mg/kg) + Tamoxifen-treated group (40×). (e) PFDB (200 mg/kg) + Tamoxifen-treated group, increased number of hepatocytes with normal nucleus (40×)