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Figure 1: Effect of ammonium glycyrrhizinate for 29 days on histopathological alteration in normal and doxorubicin injected rats (a) Control rats (b) heart tissue administered with ammonium glycyrrhizinate (50 mg/kg) + doxorubicin showing mild focal vacoulation and loss of striations (c) heart tissue administered with ammonium glycyrrhizinate (100 mg/kg) + doxorubicin showing mild vascular congestion and hemorrhage and heat muscle show vacuolation with loss of cross striations with increased cyoplasmic eosinophilia (d) Doxorubicin induced and treated with ammonium glycyrrhizinate solution (200 mg/kg) showed focal hemorrhages and less loss of striations (e) Doxorubicin induced Cardiotoxicity heart showed more number of infl ammatory cell, hemorrhage, edema and necrosis in cardiac cell (f) Ammonium glycyrrhizinate solution (100 mg/kg) showing no vacoulation, hemorrhages and loss of striations

Figure 1: Effect of ammonium glycyrrhizinate for 29 days on histopathological alteration in normal and doxorubicin injected rats (a) Control rats (b) heart tissue administered with ammonium glycyrrhizinate (50 mg/kg) + doxorubicin showing mild focal vacoulation and loss of striations (c) heart tissue administered with ammonium glycyrrhizinate (100 mg/kg) + doxorubicin showing mild vascular congestion and hemorrhage and heat muscle show vacuolation with loss of cross striations with increased cyoplasmic eosinophilia (d) Doxorubicin induced and treated with ammonium glycyrrhizinate solution (200 mg/kg) showed focal hemorrhages and less loss of striations (e) Doxorubicin induced Cardiotoxicity heart showed more number of infl ammatory cell, hemorrhage, edema and necrosis in cardiac cell (f) Ammonium glycyrrhizinate solution (100 mg/kg) showing no vacoulation, hemorrhages and loss of striations