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Figure 1: Histological analysis of representative bladder walls. (a) Control group which received only saline. (b) In group 2, ifosfamide at 400 mg/kg induced multi-layered epithelia destruction in some areas (arrow). And the cells of epithelium and connective tissue were edemetous and its chromatine were dense (stars). (c) In group 3, epitheial cells were edemetous (arrows) but there was no uroepithelial erosion. (d and e) The epithelium thickness was normal but cells were edemetous in some areas (arrows). There was no damage in uroepithelium and connective tissue were normal. (H and E, ×100)

Figure 1: Histological analysis of representative bladder walls. (a) Control group which received only saline. (b) In group 2, ifosfamide at 400 mg/kg induced multi-layered epithelia destruction in some areas (arrow). And the cells of epithelium and connective tissue were edemetous and its chromatine were dense (stars). (c) In group 3, epitheial cells were edemetous (arrows) but there was no uroepithelial erosion. (d and e) The epithelium thickness was normal but cells were edemetous in some areas (arrows). There was no damage in uroepithelium and connective tissue were normal. (H and E, ×100)