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Figure 2: Tail flick latency (TFL) of mice receiving water or sucrose solution (32%) for 12 days along with daily intraperitoneal (i.p.) injections of L-NAME (10 mg/kg) or naltrexone (20 mg/kg). Baseline and final antinociception recordings are shown. The sucrose treated-group shows higher TFLs compared to the groups receiving tap water alone or along with L-NAME or naltrexone (***P < 0.001). The group receiving sucrose and naltrexone shows higher TFLs than the group receiving water (*P < 0.05) and significantly lower values than the group receiving sucrose (¥P < 0.05)

Figure 2: Tail flick latency (TFL) of mice receiving water or sucrose solution (32%) for 12 days along with daily intraperitoneal (i.p.) injections of L-NAME (10 mg/kg) or naltrexone (20 mg/kg). Baseline and final antinociception recordings are shown. The sucrose treated-group shows higher TFLs compared to the groups receiving tap water alone or along with L-NAME or naltrexone (***<i>P</i> < 0.001). The group receiving sucrose and naltrexone shows higher TFLs than the group receiving water (*<i>P</i> < 0.05) and significantly lower values than the group receiving sucrose (¥<i>P</i> < 0.05)