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Figure 1: Effects of DT-13 on venous thrombosis by ligation of the inferior vena cava in mice and rats. (a) DT-13 (1.0, 2.0 or 4.0 mg/kg), warfarin sodium (2.0 mg/kg) or vechicle (control) were administered orally 1 h before ligation respectively. Thrombus was obtained 6 h after ligation in mice. (b) DT-13 (1.4 mg/kg) was administered orally 1 h before ligation and 17 h after ligation. Thrombus was obtained 18 h after ligation in rats. Data are expressed as mean±SD (n=18). *P<0.05 and **P<0.01, compared with control or model

Figure 1: Effects of DT-13 on venous thrombosis by ligation of the inferior vena cava in mice and rats. (a) DT-13 (1.0, 2.0 or 4.0 mg/kg), warfarin sodium (2.0 mg/kg) or vechicle (control) were administered orally 1 h before ligation respectively. Thrombus was obtained 6 h after ligation in mice. (b) DT-13 (1.4 mg/kg) was administered orally 1 h before ligation and 17 h after ligation. Thrombus was obtained 18 h after ligation in rats. Data are expressed as mean±SD (n=18). *P<0.05 and **P<0.01, compared with control or model