Figure 2: Response to colchicine or saline (control), intra-CA1, in the novelty behavior using the place conditioning task. Each animal, after being recovered, passed the task detailed in the Materials and Methods. The animals were tested in last day to evaluate a simple type of learning. Data are expressed as the score of change in seeking for the novel place and expressed as mean ± S.E.M. A difference between drug-administered groups versus the vehicle was observed. Post hoc analysis by Tukey showed the differences (*P < 0.05) to the control