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Figure 2: Photography shows, plates; A1 and A2: Sham group, B1 and B2: Control group, C1 and C2: MES 125 mg/kg, D1 and D2: MES 250 mg/kg, E1 and E2: MES 500 mg/kg; In B1 and B2 there was marked infi ltration of neutrophils, intracellular space increased and more vacuoles seen, density of cells decreased, architecture completely altered, also hemorrhage and neuronal cell death was observed in striatum. There is signifi cant reversal of damage observed in MES treated groups (C1-E2), reversal observed in treated groups

Figure 2: Photography shows, plates; A1 and A2: Sham group, B1 and B2: Control group, C1 and C2: MES 125 mg/kg, D1 and D2: MES 250 mg/kg, E1 and E2: MES 500 mg/kg; In B1 and B2 there was marked infi ltration of neutrophils, intracellular space increased and more vacuoles seen, density of cells decreased, architecture completely altered, also hemorrhage and neuronal cell death was observed in striatum. There is signifi cant reversal of damage observed in MES treated groups (C1-E2), reversal observed in treated groups