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Figure 2: Hyaluronidase (a), elastase (b) and MMP-1 (c) inhibitory activity of C. Ternatea methanol extract, ethyl acetate, n-butanol, and aqueous fractions; [values expressed are mean ± SEM (n = 3)]. Comparisons are made between the oleanolic acid vs. CTMeOH, CTEA, CTnB, and PBAQ. All the test substances (extract, fractions, and oleanolic acid standard) were diluted to 1.56, 3.12, 6.25, 12.50, 25, and 50 μg/ml concentrations for each assay. aP < 0.05, bP < 0.01, and cP < 0.001 were considered as indicative of signifi cance difference, as compared with the oleanolic acid (Dunnett test) |
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