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Figure 1: Tension (mg) produced by cumulative concentrations of calcium chloride in the absence or presence of ethanol extract of B.monniera and nifedipine in guinea-pig trachea. Control (■), 500 μg/ ml (▲), 700 μg/ml (·) of extract and nifedipine (1 × 10 -6 M, □). Values presented are mean ± S.E.M. at P < 0.05, using ANOVA followed by LSD test compared to control values. The inhibitory effect of extract on CaCl 2 was long lasting and completely reversible within 1 h. On the other hand the effect of nifedipine was revived completely only at 1 × 10 -2 M of CaCl 2

Figure 1: Tension (mg) produced by cumulative concentrations of calcium chloride in the absence or presence of ethanol extract of <i>B.monniera</i> and nifedipine in guinea-pig trachea. Control (■), 500 μg/ ml (▲), 700 μg/ml (·) of extract and nifedipine (1 × 10 <sup>-6</sup> M, □). Values presented are mean ± S.E.M. at <i>P</i> < 0.05, using ANOVA followed by LSD test compared to control values. The inhibitory effect of extract on CaCl <sub>2</sub> was long lasting and completely reversible within 1 h. On the other hand the effect of nifedipine was revived completely only at 1 × 10 <sup>-2</sup> M of CaCl <sub>2</sub>