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Figure 2: Effect of PG extracts on the pathological fi ndings in the DNCB-induced AD-like skin lesion. (A) Histological score of epidermal thickness. (B) Histological fi ndings of dorsal skin lesions (a) normal control (NC), (b) positive control (PC), (c) PG (DNCB + PG 500 mg/kg), (d) DEX (DNCB + dexamethasone 1.5 mg/kg). (C) Immunohistochemical fi nding for cytokeratin10 as a marker of differentiated keratinocyte (a) normal control (NC), (b) positive control (PC), (c) PG (DNCB + PG 300 mg/kg), (d) DEX (DNCB + dexamethasone 1.5 mg/kg). Data are presented as mean ± SEM (n = 7). *P < 0.05 vs. PC, **P < 0.01 vs. PC |
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