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Figure 1: The antinociceptive effects of different doses of morphine (2.5, 5 and 7.5 mg/kg; i.p.) at 30-min intervals by tail-fl ick (a) and hot-plate test (b). Each point represents the mean±SEM of percent of maximal possible effect (%MPE) for 6 rats. *P<0.001, **P<0.01 compared to saline-treated group

Figure 1: The antinociceptive effects of different doses of morphine (2.5, 5 and 7.5 mg/kg; i.p.) at 30-min intervals by tail-fl ick (a) and hot-plate test (b). Each point represents the mean±SEM of percent of maximal possible effect (%MPE) for 6 rats. *<i>P</i><0.001, **<i>P</i><0.01 compared to saline-treated group