Figure 1: Effect of W. calendulacea on MDA in rats subjected to global cerebral ischemia followed by reperfusion. I: Sham control, no occlusion, II: ischemic control (normal saline, 10 ml/ kg, p.o.), III: W. calendulacea (250 mg/kg, single dose/day, p.o.) + ischemia, IV: W. calendulacea (250 mg/kg, double dose/day, p.o.) + ischemia, V: W. calendulacea (500 mg/kg, single dose/day, p.o.) + ischemia, VI: W. calendulacea (500 mg/kg, double dose/day, p.o.) + ischemia. Values are expressed as mean ± S.E.M., (n = 6). a = P<0.01 vs Sham control, b = P<0.01 vs ischemic control, by one-way analysis of variance (ANOVA), followed by Dunnett t-test