Figure 4: Microscopic illustration of the liver of rats (H&E. ×200). CV: central vein. A: Group II (rats received APAP), hepatocytes show severe hydropic degeneration. Note the big spaces in cytoplasm (arrows); B: Group III (rats received APAP + deferoxamine), note the moderate cell swelling and lymphocytes in portal area (arrow and circle); C: Group IV (rats received APAP + vanadium), note the mild cell swelling. There are minute spaces in some of hepatocytes and the sinusoids are clear (arrows).