Figure 4 :Effect of E2 on prostate pathology when TP was 18.5 mg/kg/rat. Control group is picture (a) and castrated control group is picture (b). And the other 7 groups which were all administered TP 18.5 mg/kg/rat, and E2 were 0 (c), 0.4 (d), 2.0 (e), 10 (f), 50 (g), 250 (h) and 1250 μg/kg (j). Compared with the control group (a), the area of prostate glandular cavity were all significant differences. Magnification ×100.