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Figure 1: Photomicrograph of rat heart showing normal architecture with regular morphology of myocardial cell membrane and well-preserved cytoplasm (CTR group) (A), doxorubicin (DOX) treated group (DOX) showing subendocardial loss of muscles with inflammatory cells surrounded by edema (B), NAP PS group showed mild edema (C), TMZ PS group showed normal architecture without any pathological symptoms (D), photomicrograph of DOX + NAP group revealed extensive vacuolization, myofibrillar loss and edema (E) whereas DOX + TMZ group and DOX TMZ + NAP group showed mild myofibrillar loss with less extensive vacuolization (F and G) (H and E, 10).

Figure 1: Photomicrograph of rat heart showing normal architecture with regular morphology of myocardial cell membrane and well-preserved cytoplasm (CTR group) (A), doxorubicin (DOX) treated group (DOX) showing subendocardial loss of muscles with inflammatory cells surrounded by edema (B), NAP PS group showed mild edema (C), TMZ PS group showed normal architecture without any pathological symptoms (D),
photomicrograph of DOX + NAP group revealed extensive vacuolization, myofibrillar loss and edema (E) whereas DOX + TMZ group and DOX TMZ + NAP group showed mild myofibrillar loss with less extensive vacuolization (F and G) (H and E, 10).