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Figure 1: Example of standard H and E staining of aorta for evaluating atherosclerotic lesions in 2% high-cholesterol diet group. No lesions were observed in control groups. 2% high-cholesterol diet induced atherosclerotic lesions; the diameter of the internal layer was increased and the cells, due to accumulation of lipids, are seen as yellowish white. Hypertrophy of endothelial cells and accumulation of lipids in endothelial layers, with calcifi cation in the media, indicates induction of atheroma. I = intima, M = media, A = adventitia, CA = calcification area, EC = endothelial cell

Figure 1: Example of standard H and E staining of aorta for evaluating atherosclerotic lesions in 2% high-cholesterol diet group. No lesions were observed in control groups. 2% high-cholesterol diet induced atherosclerotic lesions; the diameter of the internal layer was increased and the cells, due to accumulation of lipids, are seen as yellowish white. Hypertrophy of endothelial cells and accumulation of lipids in endothelial layers, with calcifi cation in the media, indicates induction of atheroma. I = intima, M = media, A = adventitia, CA = calcification area, EC = endothelial cell