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   2002| March-April  | Volume 34 | Issue 2  
 
 
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REVIEW ARTICLE
Anti-ulcer drugs from indigenous sources with emphasis on Musa sapientum, Tamrabhasma, Asparagus racemosus and Zingiber officinale
RK Goyal, K Sairam
March-April 2002, 34(2):100-110
1. Scoparone produced a rapid and sustained fall of blood pressure in anaesthetized normotensive and experimental hypertensive animals and conscious normotensive rats. The effect was dose related, appeared immediately after i.v. and within I5-20 min after p.o. administration and lasted for 2-5 h. 2. The hypertensive animals were more sensitive to the effect of scoparone than normotensive. 3. The antihypertensive effect of scoparone appears to be the results of both the central as well as peripheral actions.
[ABSTRACT]   Full text not available  [PDF] [CITATIONS]
  4,378 982 32
EDUCATIONAL FORUM
Genotoxicity testing, a regulatory requirement for drug discovery and development: Impact of ICH guidelines
Rao P Rama, CL Kaul, GB Jena
March-April 2002, 34(2):86-89
1. In the present study it has been shown that acetylsalicylic acid (ASA) produces hemolysis of both normal and G-6-PD deficient erythrocytes. 2. The degree of hemolysis is almost the same in both the erythrocytes. 3. Acetylation and peroxidation of membrane lipid do not appear to be necessary for the hemolytic effect of ASA. 4. Severe membrane damage as evident from the liberation of phospholipids and sterols appears to be the mechanism by which ASA produces hemolysis.
[ABSTRACT]   Full text not available    [CITATIONS]
  2,312 0 11
SHORT COMMUNICATION
Effect of alcoholic extract of achyranthes bidentata blume on acute and sub acute inflammation
T Vetrichelvan, M Jagadeesan
March-April 2002, 34(2):115-118
1. Penbutolol, a new, centrally-active (-blocking agent has been studied for its interaction with alcohol. 2. Alcohol (75(proof whisky) as 0.8 mg/kg was administered with 20 mg. penbutolol or placebo in double-blind crossover to 6 volunteers. 3. Psychomotor tests of performance did not reveal any significant penbutolol-alcohol interaction. 4. Peak changes in psychomotor performance coincided under both treatment conditions with peak serum alcohol levels.
[ABSTRACT]   Full text not available  [PDF] [CITATIONS]
  1,784 225 3
EDUCATIONAL FORUM
Pharmacotherapy of glaucoma
Saxena Rohit, Prakash Jai, K Gupta Suresh, Mathur Priya
March-April 2002, 34(2):71-85
Full text not available  [PDF] [CITATIONS]
  1,636 236 7
SHORT COMMUNICATION
Drug therapy for H.pylori - are Nitroimidazoles useful in Indian patients?
P Balamourougane, S Kundargi Vinay, Kate Vikram, Ananthakrishnan
March-April 2002, 34(2):111-114
1. Scoparone produced a rapid and sustained fall of blood pressure in anaesthetized normotensive and experimental hypertensive animals and conscious normotensive rats. The effect was dose related, appeared immediately after i.v. and within I5-20 min after p.o. administration and lasted for 2-5 h. 2. The hypertensive animals were more sensitive to the effect of scoparone than normotensive. 3. The antihypertensive effect of scoparone appears to be the results of both the central as well as peripheral actions.
[ABSTRACT]   Full text not available  [PDF] [CITATIONS]
  1,540 110 1
Antianaphylactic effect of DLH-3041 (Polyherbal formulation) on rat mesenteric mast cell degranulation
K Padmalatha, BV Venkataraman, R Roopa
March-April 2002, 34(2):119-122
1. Penbutolol, a new, centrally-active (-blocking agent has been studied for its interaction with alcohol. 2. Alcohol (75(proof whisky) as 0.8 mg/kg was administered with 20 mg. penbutolol or placebo in double-blind crossover to 6 volunteers. 3. Psychomotor tests of performance did not reveal any significant penbutolol-alcohol interaction. 4. Peak changes in psychomotor performance coincided under both treatment conditions with peak serum alcohol levels.
[ABSTRACT]   Full text not available  [PDF] [CITATIONS]
  1,364 154 3
REPORT
The performance of drug information center at the University of Kansas Medical Center, Kansas city, USA - experiences and evaluations
SC Pradhan
March-April 2002, 34(2):123-129
Full text not available  [PDF] [CITATIONS]
  1,230 158 1
LETTER
Comparison of accuracy of self-report and urinanalysis results in opiate dependent patients
Dhawan Anju, Jain Raka, Maullick Pallab
March-April 2002, 34(2):130-132
Full text not available  [PDF] [CITATIONS]
  1,271 80 1
A simple method for study of microcirculation in albino mouse ear with light microscope
PSRK Haranath, MH Akhtar, SI Sharif
March-April 2002, 34(2):133-134
Full text not available  [PDF]
  1,150 95 -
CONFERENCE ABSTRACTS
XXXIV Annual conference of the Indian pharmacological society, Nagpur, January 10-12, 2002 abstracts of research papers (Part-I)
IPS
March-April 2002, 34(2):141-154
Full text not available  [PDF]
  1,041 178 -
LETTER
Cholinergic mechanism in imipramine induced antinociception - A further study
Kumar Ratnesh, Saha Lekha, Bhargava Vinod
March-April 2002, 34(2):135-136
Full text not available  [PDF]
  1,075 86 -
MOLECULES OF THE MILLENNIUM
Drugs for urological disorders
R Balaraman
March-April 2002, 34(2):137-138
Full text not available  [PDF]
  1,026 124 -
EDITORIAL
Plagiarism-II
B Gitanjali
March-April 2002, 34(2):70-70
Full text not available  [PDF]
  1,017 120 -
WEB WISE
Statistics
Singh Jatinder
March-April 2002, 34(2):139-140
Full text not available  [PDF]
  950 176 -
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