Indian Journal of Pharmacology

Bioflavonoids classification, pharmacological, biochemical effects and therapeutic potential
Narayana K Raj, Reddy M Sripal, MR Chaluvadi, DR Krishna
January-February 2001, 33(1):2-16

. Levamisole hydrochloride in low concentration (5 ng/mI) stimulated the movements of the whole worm as well as of the nerve-muscle complex of Setario cervi suspended in an isolated organ bath. At higher concentration (25 ng/mI) the response was biphasic consisting of initial stimulation followed by irreversible paralysis. The initial stimulant effect is not due to release of ACh as it is not blocked by prior addition of d-tubocurarine to the bath fluid. Levamisole in 5 x 25 mg/kg daily dose caused disappearance of microfilariae from the peripheral circulation in 7 of the 8 rats treated: The drug at this dose level had some macrofilaricidal action as well. A higher dose of 5 x 50 mg/kg daily caused complete disappearance of microfilariae from peripheral circulation of all the rats and produced a significant lethal effect on the adult worms The antifilarial efficacy of the drug needs evaluation in domestic animals and men.

[ABSTRACT] Full text not available [PDF] [CITATIONS]

196

7,488

997

Histaminergic H 3 -receptors as modulators of CNS function
Vohora Divya, SN Pal, KK Pillai
January-February 2001, 33(1):17-28

Full text not available [PDF] [CITATIONS]

5

1,905

165

One year experience of drug Information service in the NGO sector
Hazra Avijit, Sen Amitava, Roy Sushanta
January-February 2001, 33(1):44-45

Full text not available [PDF] [CITATIONS]

3

1,354

117

Drug utilization trends in clinical hospital center “KRAGUJEVAC” from 1997 to 1999
M. Jankovió Slobodan, M. Jankovió Slobodan
January-February 2001, 33(1):29-36

Full text not available [PDF] [CITATIONS]

3

1,587

178

An example of the toxic potential of traditional eye cosmetics
Vaishnav Ragini
January-February 2001, 33(1):46-48

Full text not available [PDF] [CITATIONS]

1

1,804

159

Bioequivalence study of two long acting isosorbide-5- mononitrate formulations assessed by digital pulse plethysmography:
Rani P Usha, MUR Naidu, T Vijaykumar
January-February 2001, 33(1):37-40

Full text not available [PDF] [CITATIONS]

1

1,701

176

Abstracts of research papers presented in the Annual conference of the Indian Pharmacological Society, Gandhinagar, December 28-30, 2000- Part-I
IPS
January-February 2001, 33(1):51-70

Full text not available [PDF]

-

1,260

270

Editorial
R Raveendran
January-February 2001, 33(1):1-1

Full text not available [PDF]

-

1,657

91

Involvement of opioidergic mechanisms in the antinociceptive activity of allopregnanolone
M Gambhir, PK Mediratta, KK Sharma
January-February 2001, 33(1):41-42

Full text not available [PDF]

-

1,209

92

Impact of a drug utilization evaluation program on ranitidine in a South Indian Government Hospital
George Johnson, George Johnson, B Suresh
January-February 2001, 33(1):43-43

Full text not available [PDF]

-

1,501

166

Molecules of the millennium
R Balaraman
January-February 2001, 33(1):49-49

Full text not available [PDF]

-

1,357

177

EpharNet
Singh Jatinder
January-February 2001, 33(1):50-50

Full text not available [PDF]

-

1,235

93