The effects of histamine and its antagonist on human sperm motility were studied. It was shown that; 1.Histamine increases sperm motility 2. H2 antagonist cimetidine had no effect on sperm motility and classical antihistamines decreased sperm motility. 3. The inhibition produced by H antagonists could be overcome with increasing concentrations of histamine. 4. It is postulated that histamine may play a rote in regulating sperm motility and acts through specific histaminergic receptors.

1. Salicylate pharmacokinetic parameters in six healthy and ten worm infested adults were determined after an oral dose of 1200 mg of acetylsalicylic acid. 2. The results obtained indicate that various kinetic values obtained in normal volunteers in the present study are almost similar to the data reported for European and American populations 3. Round worm infection did not alter any aspect of the handling of the drug body in a significant way. 4. Delayed elimination of the drug in patients with hookworm infection was observed.

1. Salicylate pharmacokinetic parameters in six healthy and ten worm infested adults were determined after an oral dose of 1200 mg of acetylsalicylic acid. 2. The results obtained indicate that various kinetic values obtained in normal volunteers in the present study are almost similar to the data reported for European and American populations 3. Round worm infection did not alter any aspect of the handling of the drug body in a significant way. 4. Delayed elimination of the drug in patients with hookworm infection was observed.

1. Salicylate pharmacokinetic parameters in six healthy and ten worm infested adults were determined after an oral dose of 1200 mg of acetylsalicylic acid. 2. The results obtained indicate that various kinetic values obtained in normal volunteers in the present study are almost similar to the data reported for European and American populations 3. Round worm infection did not alter any aspect of the handling of the drug body in a significant way. 4. Delayed elimination of the drug in patients with hookworm infection was observed.