Role of Vitamin D in COVID-19: Correspondence

Pathum Sookaromdee¹, Viroj Wiwanitkit²,  
¹ Private Academic Consultant, Bangkok, Thailand
² Department of Community Medicine, Dr. DY Patil University, Pune, Maharashtra, India

Correspondence Address:
Dr. Pathum Sookaromdee
Private Academic Consultant, 11 Bangkok 112 Bangkok 103320
Thailand

Full Text



Sir,

We would like to share ideas on “Evidences suggesting a possible role of Vitamin D in COVID 19: The missing link.”[1] Singh et al. concluded that “Using Vitamin D as prophylaxis and/or chemotherapeutic treatment … of Vitamin D affecting many people worldwide.”[1] We agree that Vitamin D might play a role in the management of COVID-19. Trials might be useful. Considering trial, some important concerns are hereby discussed. First, it should assess the impact of genetic polymorphism. Vitamin D-binding protein polymorphism might be associated with outcome of Vitamin D supplementation in the COVID-19 treatment.[2] Additionally, if a trial will be performed, a background Vitamin D data of subjects should be assessed.

The effect of Vitamin D in COVID-19 might also be associated with some other modifiers. Sunlight exposure and estrogen interaction should be discussed. Estradiol is also proposed for its usefulness in managing COVID-19.[3] There might be an interesting co-advantage of both Vitamin D and estradiol in the management of COVID-19.

Financial support and sponsorship

Nil.

Conflicts of interest

The authors ask for waiving for any charge for this correspondence.

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