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Year : 2020  |  Volume : 52  |  Issue : 4  |  Page : 324--330

Change in jaw occlusive power by paralysis of masseter muscle with a neuromuscular blocker: Sion's masseter muscle paralysis

Sion Jo1, Jae Baek Lee2, Youngho Jin4, Taeoh Jeong4, Jae Chol Yoon4, Boyoung Park3 
1 Department of Emergency Medicine, Chonbuk National University Hospital; Research Institute of Clinical Medicine of Chonbuk National University and Biomedical Research Institute of Chonbuk National University Hospital, Jeonju-si, Korea
2 Research Institute of Clinical Medicine of Chonbuk National University and Biomedical Research Institute of Chonbuk National University Hospital; Department of Emergency Medicine, Chonbuk National University, Jeonju-si, Korea
3 National Cancer Center, National Cancer Control Institute, Goyang-si, Kyunggi-do, Korea

Correspondence Address:
Prof. Jae Baek Lee
20, Geonjiro, Deokjin-gu, Jeonju-si, Jeollabuk-do 54907
Korea

STUDY OBJECTIVE: We aimed to determine whether jaw occlusive power decreases with the injection of neuromuscular blocking agents in masseter muscle – a method we named Sion's masseter muscle paralysis (SMP). METHODS: A randomized, placebo-controlled animal study was conducted in which researchers were blinded to group allocation. We used 12 male mongrel dogs aged 10–12 months and weighing 30–35 kg. Four groups were formed: a conventional dose (CD) group (0.004 mg/kg succinylcholine in 4 ml normal saline [NS]); a high dose (HD) group (0.04 mg/kg succinylcholine in 4 ml NS); a placebo group (4 ml NS); and no intervention group. To measure the jaw occlusive power, 1 kg weight was hung sequentially on a specifically designed device on the animal's lower jaw. At −4, −2, 0', +2, +4, +6, +8, +10, +20, and +30 min, we measured the jaw occlusive power, oxygen saturation (SpO2), and end-tidal carbon dioxide (ETCO2). RESULTS: After SMP, jaw occlusive power began to decline in CD and HD group. The arithmetical mean jaw occlusive power values at −4, −2, 0', +2, +4, +6, +8, and +10 min were 9.7, 9.7, 9.7, 8.7, 8.3, 7.3, 6.7, and 6.3 kgw in the CD group and 9.7, 9.3, 8.7, 8.0, 6.7, 5.0, 5.0, and 5.3 kgw in the HD group. No abnormalities in SpO2or ETCO2were detected. CONCLUSION: Jaw occlusive power was decreased after SMP with succinylcholine, without inducing respiratory complication.


How to cite this article:
Jo S, Lee JB, Jin Y, Jeong T, Yoon JC, Park B. Change in jaw occlusive power by paralysis of masseter muscle with a neuromuscular blocker: Sion's masseter muscle paralysis.Indian J Pharmacol 2020;52:324-330


How to cite this URL:
Jo S, Lee JB, Jin Y, Jeong T, Yoon JC, Park B. Change in jaw occlusive power by paralysis of masseter muscle with a neuromuscular blocker: Sion's masseter muscle paralysis. Indian J Pharmacol [serial online] 2020 [cited 2022 Dec 5 ];52:324-330
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=2020;volume=52;issue=4;spage=324;epage=330;aulast=Jo;type=0