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Year : 2020  |  Volume : 52  |  Issue : 4  |  Page : 254--259

Comparison of medication acceptance of intranasal midazolam administered by parents versus doctors in children – A randomized trial

M V. S Satya Prakash, S Sivasankar, Lenin Babu Elakkumanan, VK Mohan, Rithu Krishna Kamaladevi 
 Department of Anaesthesiology and CC, JIPMER, Puducherry, India

Correspondence Address:
Dr. M V. S Satya Prakash
Department of Anaesthesiology and CC, JIPMER, Puducherry
India

BACKGROUND: The positive effects of midazolam as a premedication in pediatric patients are well documented. Although there are many studies regarding the route and dosage of administration, literature does not have any evidence on the outcome of medication acceptance based on the person administering the drug. AIM: The aim of this study was to compare the medication acceptance and preoperative anxiolysis of intranasal midazolam administered by parents and anesthesiologists. MATERIALS AND METHODS: This prospective randomized study was conducted in sixty children belonging to the American Society of Anesthesiologists Class 1 or 2 belonging to either sex, aged between 1 and 9 years, undergoing elective surgeries. Group P received intranasal midazolam administered by parents, whereas Group D received intranasal midazolam administered by doctors. Various scores were assessed. RESULTS: Children were more sedated in Group P. Clinically, medication acceptance was better in Group P when compared with Group D, but a statistically significant difference in medication acceptance was seen only in patients who are >4 years of age. Parental separation, Ramsay Sedation Score, and mask acceptance were better in Group P than in Group D. CONCLUSION: Intranasal midazolam when given by parents produces better preoperative anxiolysis and easier parental separation as compared with administration by a medical staff.


How to cite this article:
Satya Prakash M V, Sivasankar S, Elakkumanan LB, Mohan V K, Kamaladevi RK. Comparison of medication acceptance of intranasal midazolam administered by parents versus doctors in children – A randomized trial.Indian J Pharmacol 2020;52:254-259


How to cite this URL:
Satya Prakash M V, Sivasankar S, Elakkumanan LB, Mohan V K, Kamaladevi RK. Comparison of medication acceptance of intranasal midazolam administered by parents versus doctors in children – A randomized trial. Indian J Pharmacol [serial online] 2020 [cited 2020 Oct 20 ];52:254-259
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=2020;volume=52;issue=4;spage=254;epage=259;aulast=Satya;type=0