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Year : 2013  |  Volume : 45  |  Issue : 1  |  Page : 93--94

Fatal anaphylactic reaction to iron sucrose in pregnancy

Ajay Mishra, Nikhil Dave, Kishor Viradiya 
 Department of Medicine, Pramukhswami Medical College, Karamsad, India

Correspondence Address:
Ajay Mishra
Department of Medicine, Pramukhswami Medical College, Karamsad
India

Iron-deficiency anemia in pregnancy can have serious deleterious effects for both mother and fetus. Parenteral iron therapy in iron-deficiency anemia is recommended in patients where oral iron therapy is ineffective due to malabsorption states and non-compliance. Compared to oral iron therapy, intravenous iron results in much more rapid resolution of iron-deficiency anemia with minimal adverse reactions. Iron sucrose has a favorable safety profile and is an alternative to other forms of parenteral iron therapy in correction of iron stores depletion. Immune mechanisms and iron agent releasing bioactive, partially unbound iron into the circulation, resulting in oxidative stress appears to cause severe adverse reactions. Although iron sucrose has a favorable safety profile in comparison to other parenteral iron preparations, this report highlights a fatal anaphylactic shock to iron sucrose in a pregnant woman with severe iron deficiency non-compliant to oral iron therapy.


How to cite this article:
Mishra A, Dave N, Viradiya K. Fatal anaphylactic reaction to iron sucrose in pregnancy.Indian J Pharmacol 2013;45:93-94


How to cite this URL:
Mishra A, Dave N, Viradiya K. Fatal anaphylactic reaction to iron sucrose in pregnancy. Indian J Pharmacol [serial online] 2013 [cited 2022 Oct 2 ];45:93-94
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=2013;volume=45;issue=1;spage=93;epage=94;aulast=Mishra;type=0