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Year : 2013  |  Volume : 45  |  Issue : 1  |  Page : 80--82

Retrospective analysis of Steven Johnson syndrome and toxic epidermal necrolysis over a period of 5 years from northern Karnataka, India

Kikkeri Narayanasetty Naveen, Varadraj V Pai, Vijetha Rai, Sharatchandra B Athanikar 
 Department of Dermatology, Sri Dharmasthala Manjunatheshwara College of Medical Sciences and Hospital (SDMCMS and H), Dharwad, Karnataka, India

Correspondence Address:
Kikkeri Narayanasetty Naveen
Department of Dermatology, Sri Dharmasthala Manjunatheshwara College of Medical Sciences and Hospital (SDMCMS and H), Dharwad, Karnataka
India

Objective: Cutaneous drug reactions are the most common type of adverse drug reactions. Adverse cutaneous drug reactions form 2-3% of the hospitalized patients. 2% of these are potentially serious. This study aims to detect the drugs commonly implicated in Steven Johnson Syndrome-Toxic Epidermal Necrosis (SJS-TEN). Materials and Methods: A retrospective analysis was done in all patients admitted in the last five years in SDM hospital with the diagnosis of SJS-TEN. Results: A total of 22 patients with SJS-TEN were studied. In 11 patients anti-epileptics was the causal drug and in 7, anti-microbials was the causal drug. Recovery was much faster in case of anti epileptics induced SJS-TEN as compared to that induced by ofloxacin. Conclusion: SJS-TEN induced by ofloxacin has a higher morbidity and mortality compared to anti convulsants.


How to cite this article:
Naveen KN, Pai VV, Rai V, Athanikar SB. Retrospective analysis of Steven Johnson syndrome and toxic epidermal necrolysis over a period of 5 years from northern Karnataka, India.Indian J Pharmacol 2013;45:80-82


How to cite this URL:
Naveen KN, Pai VV, Rai V, Athanikar SB. Retrospective analysis of Steven Johnson syndrome and toxic epidermal necrolysis over a period of 5 years from northern Karnataka, India. Indian J Pharmacol [serial online] 2013 [cited 2022 Sep 29 ];45:80-82
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=2013;volume=45;issue=1;spage=80;epage=82;aulast=Naveen;type=0