|
Trimethoprim-sulfamethoxazole-induced Steven Johnson syndrome in an HIV-infected patient
Syed Ahmed Taqi1, Syed Ahmed Zaki2, Angadi Rajasab Nilofer2, Lateef Begum Sami3
1 Department of Oral Pathology and Microbiology, Bharthi Vidyapeeth University Dental College and Hospital, Navi Mumbai, India
2 Department of Pediatrics and Obstetrics and Gynecology, Lokmanya Tilak Municipal Medical College and General Hospital, Sion, Mumbai, India
3 Department of Physiology, Mahatma Gandhi Mission Medical College and Hospital, Aurangabad, Maharashtra, India
Correspondence Address:
Syed Ahmed Zaki
Department of Pediatrics and Obstetrics and Gynecology, Lokmanya Tilak Municipal Medical College and General Hospital, Sion, Mumbai
India
Trimethoprim-sulfamethoxazole (TMP/SMX) is a widely prescribed antimicrobial for the management of several uncomplicated infections. It is commonly used for the treatment and prophylaxis of Pneumocystis jirovecii pneumonia (PCP) in the HIV-infected population. The adverse reaction to TMP/SMX is more frequent and severe in HIV-infected patients as compared to the general population. Here, we report a case of Stevens-Johnson syndrome (SJS) secondary to TMP/SMX. The patient had a generalized cutaneous reaction with involvement of the eyes, oral cavity, and genitals. He had elevated hepatic alanine aminotransferase and aspartate aminotransferase enzyme. TMP/SMX therapy was stopped and supportive treatment was started. His condition improved after eight days of stopping TMP/SMX therapy.
How to cite this article:
Taqi SA, Zaki SA, Nilofer AR, Sami LB. Trimethoprim-sulfamethoxazole-induced Steven Johnson syndrome in an HIV-infected patient.Indian J Pharmacol 2012;44:533-535
|
How to cite this URL:
Taqi SA, Zaki SA, Nilofer AR, Sami LB. Trimethoprim-sulfamethoxazole-induced Steven Johnson syndrome in an HIV-infected patient. Indian J Pharmacol [serial online] 2012 [cited 2023 Mar 30 ];44:533-535
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=2012;volume=44;issue=4;spage=533;epage=535;aulast=Taqi;type=0 |
|
