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Year : 2011  |  Volume : 43  |  Issue : 2  |  Page : 180--182

Lantana montevidensis Briq improves the aminoglycoside activity against multiresistant Escherichia coli and Staphylococcus aureus

Erlanio O Sousa1, Thiago S Almeida1, Fabíola F.G. Rodrigues1, Adriana R Campos2, Sidney G Lima3, José G.M. Costa1 
1 Molecular Bioprospection Postgraduation Program, Laboratory of Natural Products Research, Regional University of Cariri, 63105 - 000, Crato, CE, Brazil
2 Vice-Reitoria de Pesquisa e Pós-Graduação, Universidade de Fortaleza, Av. Washington Soares 1321, Edson Queiroz, 60811-905, Fortaleza-CE, Brazil
3 Departamento de Química, Universidade Federal do Piauí, Campus Universitário Ministro Petrônio Portella, 64049-550, Bairro Ininga,Teresina-PI, Brazil

Correspondence Address:
José G.M. Costa
Molecular Bioprospection Postgraduation Program, Laboratory of Natural Products Research, Regional University of Cariri, 63105 - 000, Crato, CE
Brazil

Objective : In this work, we report the antibacterial and modulatory activity of Lantana montevidensis Briq. Materials and Methods : The antibacterial activities of leaf (LELm) and root (RELm) extracts alone or in association with aminoglycosides were determined by a microdilution test. Multiresistant strains of Escherichia coli (Ec 27) and Staphylococcus aureus (Sa 358) were used. Results : The results show the inhibitory activity of LELm against E. coli (minimal inhibitory concentration [MIC] 16 μg/mL) and S. aureus (MIC 128 μg/mL). The synergistic effect of the extracts and aminoglycosides was verified too. The maximum effects were obtained with RELm with gentamicin against E. coli with MIC reduction (312 to 2 μL). Conclusion : The data from this study are indicative of the activity antibacterial of extracts of L. montevidensis and its potential in modifying the resistance of aminoglycosides.


How to cite this article:
Sousa EO, Almeida TS, Rodrigues FF, Campos AR, Lima SG, Costa JG. Lantana montevidensis Briq improves the aminoglycoside activity against multiresistant Escherichia coli and Staphylococcus aureus.Indian J Pharmacol 2011;43:180-182


How to cite this URL:
Sousa EO, Almeida TS, Rodrigues FF, Campos AR, Lima SG, Costa JG. Lantana montevidensis Briq improves the aminoglycoside activity against multiresistant Escherichia coli and Staphylococcus aureus. Indian J Pharmacol [serial online] 2011 [cited 2021 May 17 ];43:180-182
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=2011;volume=43;issue=2;spage=180;epage=182;aulast=Sousa;type=0