Indian Journal of Pharmacology Home 

CASE REPORT
[View FULLTEXT] [Download PDF]
Year : 2010  |  Volume : 42  |  Issue : 4  |  Page : 243--244

Unusual nail pigmentation following cyclophosphamide-containing chemotherapy regimen

Santosh Kumar1, Rakesh Dixit2, Saurabh Karmakar1, Sayan Paul3 
1 Department of Pulmonary Medicine, Chhatrapati Shahuji Maharaj Medical University (erstwhile King George Medical University), Lucknow, Uttar Pradesh, India
2 Department of Pharmacology and Therapeutics, Chhatrapati Shahuji Maharaj Medical University (erstwhile King George Medical University), Lucknow, Uttar Pradesh, India
3 Department of Radiotherapy, Chhatrapati Shahuji Maharaj Medical University (erstwhile King George Medical University), Lucknow, Uttar Pradesh, India

Correspondence Address:
Santosh Kumar
Department of Pulmonary Medicine, Chhatrapati Shahuji Maharaj Medical University (erstwhile King George Medical University), Lucknow, Uttar Pradesh
India

Cyclophosphamide therapy may rarely cause pigmentation of the nails which is of different patterns. We report a patient who developed pigmentation of nails after six cycles of cyclophosphamide, methotrexate, and 5-flourouracil chemotherapy, each repeated after 28 days for breast cancer. The patient developed nail pigmentation that started proximally and spread distally and involved all the nails of both hands and feet except the second and third toenails of right foot. Using Naranjo ADR Probability Scale, the case revealed a źDQ╗probableźDQ╗ association with cyclophosphamide.


How to cite this article:
Kumar S, Dixit R, Karmakar S, Paul S. Unusual nail pigmentation following cyclophosphamide-containing chemotherapy regimen.Indian J Pharmacol 2010;42:243-244


How to cite this URL:
Kumar S, Dixit R, Karmakar S, Paul S. Unusual nail pigmentation following cyclophosphamide-containing chemotherapy regimen. Indian J Pharmacol [serial online] 2010 [cited 2021 Jun 20 ];42:243-244
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=2010;volume=42;issue=4;spage=243;epage=244;aulast=Kumar;type=0