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Year : 2009  |  Volume : 41  |  Issue : 2  |  Page : 87--88

Studies on anti-inflammatory effect of aqueous extract of leaves of Holoptelea integrifolia, Planch. in rats

Shrinivas Sharma, KS Lakshmi, Arjun Patidar, Abhinav Chaudhary, Sanjay Dhaker 
 Department of Pharmacology, SRM College of Pharmacy, SRM University, SRM Nagar, Kattankulathur - 603 203, Tamil Nadu, India

Correspondence Address:
Shrinivas Sharma
Department of Pharmacology, SRM College of Pharmacy, SRM University, SRM Nagar, Kattankulathur - 603 203, Tamil Nadu
India

Objectives: The purpose of the present study was to investigate the anti-inflammatory properties of aqueous extract of the leaves of H. integrifolia, Planch. Materials and Methods: The hind paw edema was produced in rats by subplanter injection of carageenan. The aqueous extract of H. integrifolia, Planch. (AHI) at dose (250 and 500 mg/kg p.o) was given to observe % inhibition of paw edema which were comparable with indomethacin (10 mg/kg p.o) used as a reference drug. Results: The extract administered orally at doses of 250 and 500 mglkg p.o produced a significant (P < 0.05) dose dependent inhibition of edema formation Conclusions: A significant % inhibition of paw edema by the aqueous extract of leaves of H. integrifolia, Planch. and its almost nearby same % inhibition with indomethacin suggest its usefulness as an anti-inflammatory agent.


How to cite this article:
Sharma S, Lakshmi K S, Patidar A, Chaudhary A, Dhaker S. Studies on anti-inflammatory effect of aqueous extract of leaves of Holoptelea integrifolia, Planch. in rats.Indian J Pharmacol 2009;41:87-88


How to cite this URL:
Sharma S, Lakshmi K S, Patidar A, Chaudhary A, Dhaker S. Studies on anti-inflammatory effect of aqueous extract of leaves of Holoptelea integrifolia, Planch. in rats. Indian J Pharmacol [serial online] 2009 [cited 2022 Nov 29 ];41:87-88
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=2009;volume=41;issue=2;spage=87;epage=88;aulast=Sharma;type=0