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Glucagon like peptide-1: A new therapeutic target for diabetes mellitus
SK Patel1, RK Goyal2, IS Anand1, JS Shah1, HU Patel1, CN Patel1
1 Shri Sarvajanik Pharmacy College, Near Arvind Baug, Mehsana-384001, Gujarat, India
2 L.M. College of Pharmacy, Navrangpura, Ahmedabad-380009, Gujarat, India
Correspondence Address:
S K Patel
Shri Sarvajanik Pharmacy College, Near Arvind Baug, Mehsana-384001, Gujarat
India
Glucagon-like peptide-1 (GLP-1) is an endogenous peptide secreted from the gut in response to the presence of food. GLP-1 and its longer acting analog exendin-4 have multiple synergistic effects on glucose dependent, insulin secretion pathways of the pancreatic β-cell and on plasticity in neuronal cells. Recently the development of these peptides as a novel therapeutic strategy for non-insulin-dependent (type 2) diabetes mellitus and associated neuropathy has been the focus of much interest. Here we describe the biological actions of GLP-1 and its related analogs.
How to cite this article:
Patel S K, Goyal R K, Anand I S, Shah J S, Patel H U, Patel C N. Glucagon like peptide-1: A new therapeutic target for diabetes mellitus.Indian J Pharmacol 2006;38:231-237
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How to cite this URL:
Patel S K, Goyal R K, Anand I S, Shah J S, Patel H U, Patel C N. Glucagon like peptide-1: A new therapeutic target for diabetes mellitus. Indian J Pharmacol [serial online] 2006 [cited 2023 Jun 10 ];38:231-237
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=2006;volume=38;issue=4;spage=231;epage=237;aulast=Patel;type=0 |
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