Indian Journal of Pharmacology Home 

RESEARCH PAPER
[View FULLTEXT] [Download PDF]
Year : 2004  |  Volume : 36  |  Issue : 1  |  Page : 38--40

Antitumor activity of Indigofera aspalathoides on Ehrlich ascites carcinoma in mice

B Rajkapoor1, B Jayakar1, N Murugesh2 
1 Department of Pharmacology, Vinayaka Missionís College of Pharmacy, Yercaud Road, Salem - 636008, India
2 Institute of Pharmacology, Madurai Medical College, Madurai - 625020, India

Correspondence Address:
B Rajkapoor
Department of Pharmacology, Vinayaka Missionís College of Pharmacy, Yercaud Road, Salem - 636008
India

Objective: To evaluate the antitumor activity of the ethanol extract of Indigofera aspalathoides (EIA) in mice. Material and Methods: The antitumor activity of EIA was evaluated against the Ehrlich ascites carcinoma (EAC) tumor model. The activity was assessed using survival time, peritoneal cell count, hematological studies, solid tumor mass and in vitro cytotoxicity. Results: Oral administration of EIA increased the survival time and normal peritoneal cell count. Hematological parameters, protein and PCV, which were altered by tumor inoculation, were restored. Solid tumor mass was also significantly reduced. EIA was found to be cytotoxic in the in vitro model. Conclusion: EIA possesses significant antitumor activity.


How to cite this article:
Rajkapoor B, Jayakar B, Murugesh N. Antitumor activity of Indigofera aspalathoides on Ehrlich ascites carcinoma in mice.Indian J Pharmacol 2004;36:38-40


How to cite this URL:
Rajkapoor B, Jayakar B, Murugesh N. Antitumor activity of Indigofera aspalathoides on Ehrlich ascites carcinoma in mice. Indian J Pharmacol [serial online] 2004 [cited 2021 Sep 20 ];36:38-40
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=2004;volume=36;issue=1;spage=38;epage=40;aulast=Rajkapoor;type=0