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Year : 2001  |  Volume : 33  |  Issue : 6  |  Page : 445--451

A method for evaluation of variables in drug interaction

Qing-Shan Zheng1, Chang-Qing Gui2, Rui-Yuan Sun3 
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2 
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Correspondence Address:
Qing-Shan Zheng


1. The biochemical and haematological effects of tolmetin (a pyrole acetic acid derivative), on blood sugar,«SQ» serum cholesterol, serum uric acid, blood count, coagulation time, plasma fibrinogen content and euglobin clot lysis time (ELT) were studied in albino rabbits 2. Tolmetin (10 mg/kg), (P.O.) produced marked and significant hypoglycaemic, hypocholesterolaemic and hypouricaemic effects which started after one hour with a peak effect at two hours without complete recovery even upto four hours. 3. It decreased coagulation time and platelet count but increased plasma fibrinogen level and ELT.


How to cite this article:
Zheng QS, Gui CQ, Sun RY. A method for evaluation of variables in drug interaction.Indian J Pharmacol 2001;33:445-451


How to cite this URL:
Zheng QS, Gui CQ, Sun RY. A method for evaluation of variables in drug interaction. Indian J Pharmacol [serial online] 2001 [cited 2021 Oct 28 ];33:445-451
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=2001;volume=33;issue=6;spage=445;epage=451;aulast=Zheng;type=0