Indian Journal of Pharmacology Home 

RESEARCH PAPER
[Download PDF]
Year : 2000  |  Volume : 32  |  Issue : 6  |  Page : 357--360

Analgesic and antipyretic activities of Dalbergia sissoo leaves

SW Hajare1, Chandra Suresh2, SK Tandan3, J Sarma4, J Lal5, AG Telang6 
1 
2 
3 
4 
5 
6 

Correspondence Address:
S W Hajare


Objective: To evaluate the analgesic and antipyretic activities of alcoholic extract of Dalbergia sissoo leaves. Methods: The peripheral analgesic activity of Dalbergia sissoo leaves (SLE; 100, 300 and 1000 mg/kg) was studied using acetic acid induced writhing in mice and by Randall-Selitto assay. The central analgesic activity of SLE was studied using hot-plate method and tail clip test in mice. The antipyretic activity of SLE was studied in Brewer«SQ»s yeast-induced pyrexia in rats. Results: SLE significantly decreased the writhing movements in mice in acetic acid-induced writhing test. SLE (1000 mg/kg) significantly increased the pain threshold capacity in rats in Randall-Selitto assay and the reaction time in hot-plate test but not in tail-clip test. It also showed significant antipyretic activity in Brewer«SQ»s yeast-induced pyrexia in rats throughout the observation period of 6 h. Conclusion: SLE may have analgesic and antipyretic activities.


How to cite this article:
Hajare S W, Suresh C, Tandan S K, Sarma J, Lal J, Telang A G. Analgesic and antipyretic activities of Dalbergia sissoo leaves.Indian J Pharmacol 2000;32:357-360


How to cite this URL:
Hajare S W, Suresh C, Tandan S K, Sarma J, Lal J, Telang A G. Analgesic and antipyretic activities of Dalbergia sissoo leaves. Indian J Pharmacol [serial online] 2000 [cited 2022 Oct 7 ];32:357-360
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=2000;volume=32;issue=6;spage=357;epage=360;aulast=Hajare;type=0