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|Year : 2000 | Volume
| Issue : 6 | Page : 357--360
Analgesic and antipyretic activities of Dalbergia sissoo leaves
SW Hajare1, Chandra Suresh2, SK Tandan3, J Sarma4, J Lal5, AG Telang6
Objective: To evaluate the analgesic and antipyretic activities of alcoholic extract of Dalbergia sissoo leaves.
Methods: The peripheral analgesic activity of Dalbergia sissoo leaves (SLE; 100, 300 and 1000 mg/kg) was studied using acetic acid induced writhing in mice and by Randall-Selitto assay. The central analgesic activity of SLE was studied using hot-plate method and tail clip test in mice. The antipyretic activity of SLE was studied in Brewer«SQ»s yeast-induced pyrexia in rats.
Results: SLE significantly decreased the writhing movements in mice in acetic acid-induced writhing test. SLE (1000 mg/kg) significantly increased the pain threshold capacity in rats in Randall-Selitto assay and the reaction time in hot-plate test but not in tail-clip test. It also showed significant antipyretic activity in Brewer«SQ»s yeast-induced pyrexia in rats throughout the observation period of 6 h.
Conclusion: SLE may have analgesic and antipyretic activities.
S W Hajare
|How to cite this article:|
Hajare S W, Suresh C, Tandan S K, Sarma J, Lal J, Telang A G. Analgesic and antipyretic activities of Dalbergia sissoo leaves.Indian J Pharmacol 2000;32:357-360
|How to cite this URL:|
Hajare S W, Suresh C, Tandan S K, Sarma J, Lal J, Telang A G. Analgesic and antipyretic activities of Dalbergia sissoo leaves. Indian J Pharmacol [serial online] 2000 [cited 2023 Jun 3 ];32:357-360
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=2000;volume=32;issue=6;spage=357;epage=360;aulast=Hajare;type=0