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Year : 1999  |  Volume : 31  |  Issue : 3  |  Page : 229--231

Effect of gentamicin on specific immune response in rabbits

HB Asha1, gowda Honne2, K Narayana3, G Krishnappa4, K Jayakumar5 
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Correspondence Address:
H B Asha


Objective: To study the effect of gentamicin on humoral and cell mediated immune system in rabbits. Methods: Rabbits were treated with gentamicin at 4 mg/kg and 8mg/kg body weight doses for 5 days along with single intramuscular injection of 0.5 ml of Brucella plain killed antigen and humoral and cellular immune responses were measured. Results: There was no significant variation in the humoral and cellular immune response between the antigen control and the groups given gentamicin along with antigen. Conclusion: Gentamicin at the two dose levels used for 5 days, in rabbits, did not affect the specific immune response.


How to cite this article:
Asha H B, Honne g, Narayana K, Krishnappa G, Jayakumar K. Effect of gentamicin on specific immune response in rabbits.Indian J Pharmacol 1999;31:229-231


How to cite this URL:
Asha H B, Honne g, Narayana K, Krishnappa G, Jayakumar K. Effect of gentamicin on specific immune response in rabbits. Indian J Pharmacol [serial online] 1999 [cited 2022 Aug 12 ];31:229-231
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1999;volume=31;issue=3;spage=229;epage=231;aulast=Asha;type=0