Indian Journal of Pharmacology Home 

RESEARCH PAPER
[Download PDF]
Year : 1997  |  Volume : 29  |  Issue : 5  |  Page : 301--305

In vitro studies on antimutagenicity of water, alcoholic and oil extracts of Semecarpus anacardium

AB Kothari1, M Lahiri2, SD Ghaisas3, SV Bhide4 
1 
2 
3 
4 

Correspondence Address:
A B Kothari


Objects: To test the antimutagenecity of water alcoholic and oil extracts of Semecarpus anacardium. Methods: Water, alcoholic and oil extracts were prepared and tested in the bacterial test system using Salmonella typhimuriurn strains TA96 and TA100 in the presence and absence of metabolic activities. The antimutagenecity was tested versus Benso(a)pyrene (BzP) in dose dependent manner. Alcoholic and water extracts were also tested in human lymphocyte in vitro for its antimutagenic activity versus BzP at concentration of 1OOOg per tube. Results: The water, alcoholic and oil extracts of Semecarpus anacardium were antimutagenic versus BzP in a dose dependent manner. The water and alcoholic extracts were antimutagenic versus BzP induced micronuclei at concentrations of 1OOOg per tube in human lymphocytes. Conclusion: Water, alcoholic and oil extracts of S. anacardium are antimutagenic against BzP induced mutagenecity.


How to cite this article:
Kothari A B, Lahiri M, Ghaisas S D, Bhide S V. In vitro studies on antimutagenicity of water, alcoholic and oil extracts of Semecarpus anacardium.Indian J Pharmacol 1997;29:301-305


How to cite this URL:
Kothari A B, Lahiri M, Ghaisas S D, Bhide S V. In vitro studies on antimutagenicity of water, alcoholic and oil extracts of Semecarpus anacardium. Indian J Pharmacol [serial online] 1997 [cited 2021 Dec 5 ];29:301-305
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1997;volume=29;issue=5;spage=301;epage=305;aulast=Kothari;type=0