Indian Journal of Pharmacology Home 

SHORT COMMUNICATION
[Download PDF]
Year : 1996  |  Volume : 28  |  Issue : 3  |  Page : 188--190

The modulating effect of glutathione on lipid peroxidation in rats treated with anticancer drugs and x-ray irradiation

G Muralikrishnan1, Devi CS Shyamala2 
1 
2 

Correspondence Address:
G Muralikrishnan


The protective effect of glutathione was assessed against cytotoxic antitumour agents like cyclophosphamide, methotrexate, 5-fluorouracil (CMF) and X-ray irradiated rats. Glutathione supplementation into the CMF and X-ray irradiated rats showed decrease in the level of thiobarbituric acid reacting substances (TBARS) in plasma, liver and intestine. It was increased in the lung even after receiving the glutathione. The level of antioxidant enzymes were restored in the RBC hemolysate.


How to cite this article:
Muralikrishnan G, Shyamala DC. The modulating effect of glutathione on lipid peroxidation in rats treated with anticancer drugs and x-ray irradiation.Indian J Pharmacol 1996;28:188-190


How to cite this URL:
Muralikrishnan G, Shyamala DC. The modulating effect of glutathione on lipid peroxidation in rats treated with anticancer drugs and x-ray irradiation. Indian J Pharmacol [serial online] 1996 [cited 2021 Sep 24 ];28:188-190
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1996;volume=28;issue=3;spage=188;epage=190;aulast=Muralikrishnan;type=0