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| Year : 1995 | Volume
: 27
| Issue : 2 | Page : 133--135 |
Beneficial effect of low dose felodipine on serum cholesterol of rabbits fed on atherogenic diet
Rekha Swain Trupti1, M Das2, S Kanungo3, J Patanaik4
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Correspondence Address:
Rekha Swain Trupti
The effect of low dose felodipine on serum cholesterol of rabbits fed on atherogenic diet was studied. Total plasma cholesterol was estimated at the beginning and at the end of 10 weeks of diet/drug administration. There was a significant increase in mean serum cholesterol level of rabbits receiving atherogenic diet with vehicle from 62.23( 5.12 mg/dl to 165.75( 13.62 mg/dl, whereas corresponding values for the rabbits receiving atherogenic diet with felodipine was from 66.55(4.53 mg/dl to 100.5% 6.91 mg/dl. The rise in 10 weeks serum cholesterol level in latter group was significantly low (P < 0.001). The drug/vehicle has no significant effect on serum cholesterol of rabbits receiving standard diet. Thus early low dose felodipine has a significant cholesterol lowering effect.
How to cite this article:
Trupti RS, Das M, Kanungo S, Patanaik J. Beneficial effect of low dose felodipine on serum cholesterol of rabbits fed on atherogenic diet.Indian J Pharmacol 1995;27:133-135
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How to cite this URL:
Trupti RS, Das M, Kanungo S, Patanaik J. Beneficial effect of low dose felodipine on serum cholesterol of rabbits fed on atherogenic diet. Indian J Pharmacol [serial online] 1995 [cited 2023 May 28 ];27:133-135
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1995;volume=27;issue=2;spage=133;epage=135;aulast=Trupti;type=0 |
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