Indian Journal of Pharmacology Home 

[Download PDF]
Year : 1994  |  Volume : 26  |  Issue : 2  |  Page : 153--155

Antidipsogenic action of alpha methyldopa

AK Khare1, J Mambwe2 

Correspondence Address:
A K Khare

Acute peripheral administration of methyldopa (20 mg/kg, i.p.) attenuates drinking response in rats to acute peripheral administration of either isoproternol (25(g/kg bw, s.c.) or hypertonic saline (5 ml/kg bw, i.p.) solution. This antidipsogenic action was not different from that of acute peripheral administration of clonidine (12 (g/kg bw, i.p.). These results suggest that methyldopa has antidipsogenic effect similar to clonidine and support the view that alpha2 adrenoceptors on neuraxis are involved in mediating this effect.

How to cite this article:
Khare A K, Mambwe J. Antidipsogenic action of alpha methyldopa.Indian J Pharmacol 1994;26:153-155

How to cite this URL:
Khare A K, Mambwe J. Antidipsogenic action of alpha methyldopa. Indian J Pharmacol [serial online] 1994 [cited 2022 Aug 18 ];26:153-155
Available from:;year=1994;volume=26;issue=2;spage=153;epage=155;aulast=Khare;type=0