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Year : 1993  |  Volume : 25  |  Issue : 4  |  Page : 215--219

IgG.subclass response to cell - and egg grown influenza vaccines in human volunteers

Ahmeida ETS Ben1, R Jennings2, CW Potter3 
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2 
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Correspondence Address:
Ahmeida ETS Ben


The immunogenicity of two inactivated influenza A (H1 N1) vaccines which were derived either as tissue culture strains in MDCK cells or eggs from virus grown from a single clinical specimen was assessed in a comparative study. An ELISA was used to measure serum IgG and IgG subclass antibody responses in grouped volunteers receiving the vaccines. Both types of vaccines were able to stimulate production of IgG and IgG subclass antibody response, predominantly IgG1 and to a lesser extent lgG3. The results suggest that despite the antigenic differences of the two vaccine virus strains used in this study similar IgG responses were evoked.


How to cite this article:
Ben AE, Jennings R, Potter C W. IgG.subclass response to cell - and egg grown influenza vaccines in human volunteers.Indian J Pharmacol 1993;25:215-219


How to cite this URL:
Ben AE, Jennings R, Potter C W. IgG.subclass response to cell - and egg grown influenza vaccines in human volunteers. Indian J Pharmacol [serial online] 1993 [cited 2023 Jan 29 ];25:215-219
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1993;volume=25;issue=4;spage=215;epage=219;aulast=Ben;type=0