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Year : 1992  |  Volume : 24  |  Issue : 2  |  Page : 98--101

Efficacy of an ayurvedic formulation in rheumatoid arthritis: A double-blind, placebo-controlled, cross-over study

RR Kulkarni1, PS Patki2, VP Jog3, Gandage4, B Patwardban5 
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Correspondence Address:
R R Kulkarni


The clinical efficacy of an Ayurvedic indigenous formulation containing Withania somnifera, Boswellia serrata, Curcuma longa and zinc, was evaluated in a randomized, double-blind, placebo controlled, cross-over study in 20 patients of rheumatoid arthritis. Treatment with the indigenous formulation for the period of 3 months produced significantly greater relief of pain, decreased morning stiffness, decrease in Ritche articular index and joint score. A significant drop in erythrocyte sedimentation rate was observed in the drug treated patients (P < 0.01). Nine out of 20 patients showed seroconversion at the end of three months treatment with indigenous drug. Radiological assessment, however, did not show any significant changes in both the groups. Side effects observed with this formulation did not necesitate withdrawal of treatment.


How to cite this article:
Kulkarni R R, Patki P S, Jog V P, Gandage, Patwardban B. Efficacy of an ayurvedic formulation in rheumatoid arthritis: A double-blind, placebo-controlled, cross-over study.Indian J Pharmacol 1992;24:98-101


How to cite this URL:
Kulkarni R R, Patki P S, Jog V P, Gandage, Patwardban B. Efficacy of an ayurvedic formulation in rheumatoid arthritis: A double-blind, placebo-controlled, cross-over study. Indian J Pharmacol [serial online] 1992 [cited 2022 Jul 6 ];24:98-101
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1992;volume=24;issue=2;spage=98;epage=101;aulast=Kulkarni;type=0