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Year : 1992  |  Volume : 24  |  Issue : 2  |  Page : 126--127

Effects of drugs on mucociliary activity in humans

SU Vora1, PD Karnad2, NA Kshirsagar3 
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2 
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Correspondence Address:
S U Vora


The mucociliary transport system is an important defense mechanism of the body. Many diseases that can affect the bronchial tract may impair this system and many pharmacological agents may alter mucociliary activity. Because of the importance of this system, it was thought to be interesting to study mucociliary transport time in healthy volunteers and the effects of ibuprofen, erythromycin and theophylline on the same. Seven volunteers were selected for studying the effect of theophylline, and 20 volunteers were selected for studying the effects of ibuprofen and erythromycin, 10 volunteers for each drug. It was found that theophylline significantly improved ciliary function, whereas ibuprofen and erythromycin did not Influence ciliary function to a great extent.


How to cite this article:
Vora S U, Karnad P D, Kshirsagar N A. Effects of drugs on mucociliary activity in humans.Indian J Pharmacol 1992;24:126-127


How to cite this URL:
Vora S U, Karnad P D, Kshirsagar N A. Effects of drugs on mucociliary activity in humans. Indian J Pharmacol [serial online] 1992 [cited 2022 Jul 4 ];24:126-127
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1992;volume=24;issue=2;spage=126;epage=127;aulast=Vora;type=0