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Year : 1992  |  Volume : 24  |  Issue : 2  |  Page : 123--125

Pharmacokinetics of amikacin sulphate in goats

RP Uppal1, SP Verma2, RK Roy3, SK Garg4 
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Correspondence Address:
R P Uppal


Pharmacokinetics of amikacin sulphate in goats was investigated following single i.v. injection of 10 mg/kg. Distribution and elimination half-lives and apparent volume of distribution values were 15.7 min, 130.1 min and 0.40 I/kg, respectively. At 6 h after the administration of drug, 10.2 percent was in the central and peripheral compartments and about 90 percent had been eliminated. To produce an average steady-state plasma amikacin concentration within the therapeutic range, a dosage of 10 mg of amikacin per kg, at 12 h interval, is recommended.


How to cite this article:
Uppal R P, Verma S P, Roy R K, Garg S K. Pharmacokinetics of amikacin sulphate in goats.Indian J Pharmacol 1992;24:123-125


How to cite this URL:
Uppal R P, Verma S P, Roy R K, Garg S K. Pharmacokinetics of amikacin sulphate in goats. Indian J Pharmacol [serial online] 1992 [cited 2022 Jul 1 ];24:123-125
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1992;volume=24;issue=2;spage=123;epage=125;aulast=Uppal;type=0